CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.,Nature Methods

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CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Nature Methods ( IF 36.1 ) Pub Date : 2018-11-30 , DOI: 10.1038/s41592-018-0225-6
Jonathan Y Hsu _{1,

2} , Charles P Fulco _{3,

4} , Mitchel A Cole _{5,

6,

7} , Matthew C Canver _{2,

5,

6,

7} , Danilo Pellin _{8,

9} , Falak Sher _{5,

6,

7} , Rick Farouni _{2,

3,

10} , Kendell Clement _{2,

3,

10} , Jimmy A Guo ₂ , Luca Biasco _{8,

9} , Stuart H Orkin _{5,

6,

7,

11} , Jesse M Engreitz _{3,

12} , Eric S Lander _{3,

4,

13} , J Keith Joung _{2,

10} , Daniel E Bauer _{5,

6,

7} , Luca Pinello _{2,

3,

10}

Affiliation

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Gene Therapy Program, Harvard Medical School, Boston, MA, USA.
Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
Department of Pathology, Harvard Medical School, Boston, MA, USA.
Howard Hughes Medical Institute, Boston, MA, USA.
Harvard Society of Fellows, Harvard University, Cambridge, MA, USA.
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.