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Biomedical Applications of Chitosan Electrospun Nanofibers as a Green Polymer – Review
Carbohydrate Polymers ( IF 10.7 ) Pub Date : 2018-12-08 , DOI: 10.1016/j.carbpol.2018.12.011
Katayoon Kalantari , Amalina M. Afifi , Hossein Jahangirian , Thomas J. Webster

This review outlines new developments in the biomedical applications of environmentally friendly ('green') chitosan and chitosan-blend electrospun nanofibers. In recent years, research in functionalized nanofibers has contributed to the development of new drug delivery systems and improved scaffolds for regenerative medicine, which is currently one of the most rapidly growing fields in all of the life sciences. Chitosan is a biopolymer with non-toxic, antibacterial, biodegradable and biocompatible properties. Due to these properties, they are widely applied for biomedical applications such as drug delivery, tissue engineering scaffolds, wound dressings, and antibacterial coatings. Electrospinning is a novel technique for chitosan nanofiber fabrication. These nanofibers can be used in unique applications in biomedical fields due to their high surface area and porosity. The present work reviews recent reports on the biomedical applications of chitosan-based nanofibers in detail.



中文翻译:

壳聚糖电纺纳米纤维作为绿色聚合物的生物医学应用–综述

这篇综述概述了环保(“绿色”)壳聚糖和壳聚糖混纺电纺纳米纤维在生物医学应用中的新发展。近年来,功能化纳米纤维的研究促进了新药递送系统和再生医学改良支架的开发,再生医学目前是所有生命科学中发展最快的领域之一。壳聚糖是具有无毒,抗菌,可生物降解和生物相容性的生物聚合物。由于这些特性,它们被广泛应用于生物医学应用,例如药物输送,组织工程支架,伤口敷料和抗菌涂层。电纺丝是壳聚糖纳米纤维制造的一种新技术。这些纳米纤维具有高的表面积和孔隙率,可用于生物医学领域的独特应用。本工作详细审查了基于壳聚糖的纳米纤维的生物医学应用的最新报告。

更新日期:2018-12-08
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