Magnetic Nanomaterials for Advanced Regenerative Medicine: The Promise and Challenges.,Advanced Materials

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Magnetic Nanomaterials for Advanced Regenerative Medicine: The Promise and Challenges.
Advanced Materials ( IF 27.4 ) Pub Date : 2018-12-04 , DOI: 10.1002/adma.201804922
Xiao-Li Liu _{1,

2} , Shizhu Chen _{1,

2,

3} , Huan Zhang ₄ , Jin Zhou ₅ , Hai-Ming Fan ₄ , Xing-Jie Liang _{1,

2}

Affiliation

The recent emergence of numerous nanotechnologies is expected to facilitate the development of regenerative medicine, which is a tissue regeneration technique based on the replacement/repair of diseased tissue or organs to restore the function of lost, damaged, and aging cells in the human body. In particular, the unique magnetic properties and specific dimensions of magnetic nanomaterials make them promising innovative components capable of significantly advancing the field of tissue regeneration. Their potential applications in tissue regeneration are the focus here, beginning with the fundamentals of magnetic nanomaterials. How nanomaterials-both those that are intrinsically magnetic and those that respond to an externally applied magnetic field-can enhance the efficiency of tissue regeneration is also described. Applications including magnetically controlled cargo delivery and release, real-time visualization and tracking of transplanted cells, magnetic regulation of cell proliferation/differentiation, and magnetic activation of targeted ion channels and signal pathways involved in regeneration are highlighted, and comments on the perspectives and challenges in magnetic nanomaterial-based tissue regeneration are given.

中文翻译：

先进再生医学的磁性纳米材料：无极与挑战。

预计最近出现的许多纳米技术将促进再生医学的发展，再生医学是一种基于再生/修复患病组织或器官的组织再生技术，以恢复人体丢失，受损和衰老的细胞的功能。尤其是，磁性纳米材料的独特磁性和特定尺寸使其成为有前途的创新组件，能够显着推进组织再生领域。从磁性纳米材料的基本原理开始，它们在组织再生中的潜在应用便成为本文的重点。还描述了纳米材料（本质上是磁性的以及响应外部施加的磁场的纳米材料）如何提高组织再生的效率。

更新日期：2019-11-06

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