The interest of food industry to merchandise natural astaxanthin is growing up. However, it confronts scientific and technological challenges mainly related to its poor water solubility and chemical instability. Here, we present a new quick and efficient green process to simultaneously extract, encapsulate and stabilize astaxanthin from Haematococcus pluvialis. The process is based on the hitherto unexplored combination of supramolecular solvents (SUPRAS), nanostructured liquids generated from amphiphiles through sequential self-assembly and coacervation, and nanostructured lipid carriers (NLCs). These novel nanosystems were characterized by means of dynamic light scattering, AFM and cryoSEM, revealing spherical particles of ∼100 nm. Their antioxidant activity was measured by ORAC (20.6 ± 3.9 μM TE) and α-TEAC (2.92 ± 0.58 µM α-TE) assays and their in vitro capacity to inhibit ROS by DHE probe. Results showed that the SUPRAS-NLCs proposed yield high extraction and encapsulation efficiencies (71 ± 4%) in combination with a remarkable time stability (180 d, 4 °C).

食品工业对天然虾青素商品化的兴趣正在增长。但是，它面临着主要由于其水溶性差和化学不稳定性而引起的科学和技术挑战。在这里，我们提出了一种新的快速有效的绿色工艺，可以同时提取，封装和稳定雨生红球菌中的虾青素。。该过程基于迄今尚未探索的超分子溶剂（SUPRAS），由两亲物通过顺序自组装和凝聚产生的纳米结构液体以及纳米结构脂质载体（NLC）的组合。这些新颖的纳米系统通过动态光散射，AFM和cryoSEM进行表征，揭示了约100 nm的球形颗粒。通过ORAC（20.6±3.9μMTE）和α-TEAC（2.92±0.58μMα-TE）测定法测定其抗氧化活性，并通过DHE探针体外抑制ROS的能力。结果表明，提出的SUPRAS-NLC具有较高的提取和包封效率（71±4％），并具有显着的时间稳定性（180 d，4°C）。