As the name suggests, drug repurposing is a strategy to identify new therapeutic uses for marketed drugs, discontinued and/or shelved drugs, and drug candidates currently in clinical development. Although not a recent concept, drug repurposing has gained momentum over the past few years and several drugs have been successfully repurposed. Here, we summarize the drug repurposing landscape from 2012 to 2017, with a major focus on repurposed drugs, collaborative opportunities, and funding opportunities specific to drug repurposing projects. Along with success stories, we also highlight the challenges and limitations associated with drug repurposing.

顾名思义，药物再利用是一种策略，用于确定市售药物，已停产和/或搁置的药物以及当前正在临床开发中的候选药物的新治疗用途。尽管不是最近的概念，但在过去的几年中，重新利用毒品的势头有所增强，并且已经成功地重新利用了几种毒品。在这里，我们总结了2012年至2017年的毒品重用前景，重点关注了针对毒品重用项目的重新用途毒品，合作机会和融资机会。除成功案例外，我们还将重点介绍与药物再利用相关的挑战和局限性。