Abstract Poly(glycidyl methacrylate) (PGMA) homopolymer, poly(ethylene glycol)methyl ether-block-poly(glycidyl methacrylate) (MPEG-b-PGMA), poly(methyl methacrylate)-block-poly(glycidyl methacrylate) (PMMA-b-PGMA) diblock copolymers, and poly(ethylene glycol)methyl ether-block-poly(glycidyl methacrylate)-block-poly(methyl methacrylate) (MPEG-b-PGMA-b-PMMA) triblock copolymers with different molecular weights and polymerization degrees were successfully synthesized via atom transfer radical polymerization. Epoxy groups of PGMA blocks were converted to hydroxyl and tertiary amine residues by reacting with secondary amines (morpholine, 1-methylpiperazine and diethyl amine) over a ring-opening reaction. Additionally, derivative (co)polymers containing poly(2-hydroxy-3-methyl piperazinepropyl methacrylate) (PHMPPMA) have also been quaternized with different alkyl and aryl halides. Aqueous solution behaviours of resulting functional polymers including poly(3-diethylamino-2-hydroxypropyl methacrylate) (PDEAHPMA), poly(2-hydroxy-3-morpholinepropyl methacrylate) (PHMPMA), PHMPPMA and its quaternarnized form PQHMPPMA homopolymers and their block copolymers with MPEG and/or PMMA were investigated by varying solution conditions such as pH, ionic strength and temperature. Their solution behaviours were investigated by using proton nuclear magnetic resonance spectroscopy and dynamic light scattering techniques.

中文翻译：

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基于甲基丙烯酸缩水甘油酯的嵌段共聚物的改性及其水溶液行为

摘要 聚（甲基丙烯酸缩水甘油酯）（PGMA）均聚物、聚（乙二醇）甲基醚-嵌段-聚（甲基丙烯酸缩水甘油酯）（MPEG-b-PGMA）、聚（甲基丙烯酸甲酯）-嵌段-聚（甲基丙烯酸缩水甘油酯）（PMMA- b-PGMA）二嵌段共聚物，以及聚（乙二醇）甲基醚-嵌段-聚（甲基丙烯酸缩水甘油酯）-嵌段-聚（甲基丙烯酸甲酯）（MPEG-b-PGMA-b-PMMA）三嵌段共聚物，具有不同的分子量和聚合通过原子转移自由基聚合成功合成了度。通过在开环反应中与仲胺（吗啉、1-甲基哌嗪和二乙胺）反应，PGMA 嵌段的环氧基被转化为羟基和叔胺残基。此外，含有聚（2-羟基-3-甲基哌嗪丙酯）（PHMPPMA）的衍生（共）聚合物也已用不同的烷基和芳基卤化物进行季铵化。所得功能聚合物的水溶液行为，包括聚（3-二乙基氨基-2-羟丙基甲基丙烯酸酯）（PDEAHPMA）、聚（2-羟基-3-吗啉丙基甲基丙烯酸酯）（PHMPMA）、PHMPMA 及其季铵化形式 PQHMPPMA 均聚物及其嵌段共聚物MPEG 和/或 PMMA 通过改变溶液条件（例如 pH、离子强度和温度）进行研究。通过使用质子核磁共振光谱和动态光散射技术研究了它们的溶液行为。聚（2-羟基-3-吗啉丙基甲基丙烯酸酯）（PHMPMA）、PHMPPMA 及其季铵化形式 PQHMPPMA 均聚物及其与 MPEG 和/或 PMMA 的嵌段共聚物通过不同的溶液条件（如 pH、离子强度和温度）进行了研究。通过使用质子核磁共振光谱和动态光散射技术研究了它们的溶液行为。聚（2-羟基-3-吗啉丙基甲基丙烯酸酯）（PHMPMA）、PHMPMA 及其季铵化形式 PQHMPPMA 均聚物及其与 MPEG 和/或 PMMA 的嵌段共聚物通过不同的溶液条件（例如 pH、离子强度和温度）进行了研究。通过使用质子核磁共振光谱和动态光散射技术研究了它们的溶液行为。