Nature Methods ( IF 36.1 ) Pub Date : 2018-11-26 , DOI: 10.1038/s41592-018-0222-9 Adem Ozcelik 1 , Joseph Rufo 1 , Feng Guo 2 , Yuyang Gu 1 , Peng Li 2 , James Lata 2 , Tony Jun Huang 1, 2
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Acoustic tweezers are a versatile set of tools that use sound waves to manipulate bioparticles ranging from nanometer-sized extracellular vesicles to millimeter-sized multicellular organisms. Over the past several decades, the capabilities of acoustic tweezers have expanded from simplistic particle trapping to precise rotation and translation of cells and organisms in three dimensions. Recent advances have led to reconfigured acoustic tweezers that are capable of separating, enriching, and patterning bioparticles in complex solutions. Here, we review the history and fundamentals of acoustic-tweezer technology and summarize recent breakthroughs.
中文翻译：
用于生命科学的声学镊子。
声学镊子是一套多功能的工具，它们使用声波来操纵生物颗粒，范围从纳米大小的细胞外囊泡到毫米大小的多细胞生物。在过去的几十年中，声学镊子的功能已经从简单的粒子捕获扩展到了三维的细胞和生物体的精确旋转和平移。最近的进展已导致重新构造了声学镊子，该镊子能够在复杂溶液中分离，富集和构图生物颗粒。在这里，我们回顾了声镊技术的历史和基本原理，并总结了最新的突破。
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