Abstract A cationic gemini surfactant templated magnetic cubic mesoporous silica Fe3O4@14-3-14-MCM-48 nanocomposite was successfully synthesized and utilized in the magnetic dispersive solid phase extraction (MDSPE) of nine endocrine-disrupting compounds (EDCs) from the migrants of food contact materials by high performance liquid chromatography with diode array detection (HPLC–DAD). Fe3O4@14-3-14-MCM-48 can interact with EDCs through electrostatic interactions, hydrophobic effect, and hydrogen bonding effect. It showed excellent adsorption performance for EDCs with short alkyl chain phenols, which showed higher hydrophilicity and less retained by normal mesoporous silica with single chain surfactant as template. The parameters affecting MDSPE efficiency were optimized, and the optimum extraction conditions were adsorbent amount, 20 mg; elution solvent, methanol/acetonitrile mixture at 50/50 (v/v); NaCl concentration, 30 g/L; sample pH 5.0. Under the optimized condition, the limits of detection and limits of quantification were in the range of 1.0–2.5 and 2.9–7.5 ng/mL, respectively. Good linearity was observed in the range of 10–200.0 ng/mL with correlation coefficients of >0.997 and the recoveries were in the range of 92.6–102.3%. The developed method was successfully applied to the detection of phenolic EDCs migrants from food contact materials.

中文翻译：

---

阳离子双子表面活性剂模板化磁性立方介孔二氧化硅及其在磁性分散固相萃取食品接触材料迁移物中内分泌干扰化合物中的应用

摘要 以阳离子双子表面活性剂为模板的磁性立方介孔二氧化硅 Fe3O4@14-3-14-MCM-48 纳米复合材料被成功合成并用于磁分散固相萃取 (MDSPE) 从迁移中提取九种内分泌干扰化合物 (EDCs)。使用二极管阵列检测器的高效液相色谱法 (HPLC-DAD) 检测食品接触材料。Fe3O4@14-3-14-MCM-48可以通过静电相互作用、疏水作用和氢键作用与EDCs相互作用。它对含有短烷基链酚的 EDCs 表现出优异的吸附性能，表现出更高的亲水性，并且以单链表面活性剂为模板的普通介孔二氧化硅对EDC 的保留较少。对影响MDSPE效率的参数进行了优化，最佳萃取条件为吸附剂用量20 mg；洗脱溶剂，50/50 (v/v) 的甲醇/乙腈混合物；NaCl浓度，30克/升；样品 pH 值 5.0。在优化条件下，检测限和定量限分别在1.0-2.5和2.9-7.5 ng/mL范围内。在 10–200.0 ng/mL 范围内观察到良好的线性，相关系数 >0.997，回收率在 92.6–102.3% 范围内。所开发的方法已成功应用于检测食品接触材料中的酚类 EDCs 迁移物。0 ng/mL，相关系数 >0.997，回收率在 92.6-102.3% 范围内。所开发的方法已成功应用于检测食品接触材料中的酚类 EDCs 迁移物。0 ng/mL，相关系数 >0.997，回收率在 92.6-102.3% 范围内。所开发的方法已成功应用于检测食品接触材料中的酚类 EDCs 迁移物。