Development of a FRET-based ratiometric fluorescent probe to monitor the changes in palladium(ii) in aqueous solution and living cells†,New Journal of Chemistry

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Development of a FRET-based ratiometric fluorescent probe to monitor the changes in palladium(ii) in aqueous solution and living cells†
New Journal of Chemistry ( IF 2.7 ) Pub Date : 2018-11-22 00:00:00 , DOI: 10.1039/c8nj04866e
Li Wang _{1,

2,

3,

4,

5} , Mingguang Ren _{1,

2,

3,

4,

5} , Zihong Li _{1,

2,

3,

4,

5} , Lixuan Dai _{1,

2,

3,

4,

5} , Weiying Lin _{1,

2,

3,

4,

5}

Affiliation

The enrichment of palladium ions in organisms can harm organisms to a great extent. It is necessary and critical to develop molecular tools that can ratiometrically image Pd²⁺ in living cells. Herein, we have developed a new FRET-based ratiometric fluorescent probe (CR-Pd) for the specific determination of Pd²⁺ in living cells. Moreover, fluorescence imaging shows that CR-Pd could be used as a probe for the ratiometric visualization of Pd²⁺ in mitochondria.

中文翻译：

基于FRET的比例荧光探针的开发，可监测水溶液和活细胞中钯（ii）的变化†

生物体中钯离子的富集可在很大程度上损害生物体。开发能够按比例成像活细胞中Pd ^2+的分子工具是必要且至关重要的。本文中，我们开发了一种新的基于FRET的比例荧光探针（CR-Pd），用于特异性测定活细胞中的Pd ²⁺。此外，荧光成像表明CR-Pd可以用作线粒体中Pd ²⁺比例可视化的探针。

更新日期：2018-11-22

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