Ultrasound-assisted extraction (UAE) technology was used for extracting effective components from pomegranate (Punica granatum L.variety SisheKape-Ferdos) peel (POP). A response surface method was used to investigate the effects of independent process variables (ultrasonic amplitude (power control, UA): 20, 60 and 100%, and ultrasonic exposure time (UET): 5, 10 and 15 min) on the yield (Y) and antioxidant characteristics: total phenolic compounds (TPC), 1,1-diphenyl-2-picrylhydrazyl free radical scavenging (DPPH), ferric reducing-antioxidant power (FRAP), half maximal of radical-scavenging activity (IC₅₀) of aqueous pomegranate peel extract. According to Derringer's desired function approach, the optimal conditions based on both individual and combinations of all process variables were UA 60% and UET 6.2 min, and at this optimum condition, the predicted maximum values of Y, TPC, DPPH, FRAP, and IC₅₀ of the pomegranate peel extract (POPx) were 13.1%, 42.2 mg GA/g, 88.8%, 1824.6 μmol Fe²⁺/g, and 0.51 mg/mL, respectively. The experimental values were in a good agreement with the predicted values. Also, at optimal conditions, the minimum inhibitory concentration (MIC) of the extract (mean diameter of inhibition zone: 17.7 mm) showed that it had antifungal activities against Aspergillus niger.

超声辅助提取（UAE）技术被用于从石榴提取有效成分（石榴L.品种SisheKape-Ferdos）剥离（POP）。响应面方法用于研究独立工艺变量（超声振幅（功率控制，UA）：20％，60％和100％，超声暴露时间（UET）：5、10和15分钟）对产量的影响（ Y）和抗氧化剂特性：总酚类化合物（TPC），1,1-二苯基-2-吡啶并肼基自由基清除剂（DPPH），三价铁还原抗氧化剂能力（FRAP），最大清除自由基活性的一半（IC ₅₀）石榴皮果皮提取物。根据Derringer的期望函数方法，基于单个和所有过程变量组合的最佳条件是UA 60％和UET 6.2分钟，在此最佳条件下，Y，TPC，DPPH，FRAP和IC的预测最大值石榴皮提取物（POPx）中的₅₀分别为13.1％，42.2 mg GA / g，88.8％，1824.6μmolFe ²⁺ / g和0.51 mg / mL。实验值与预测值非常吻合。同样，在最佳条件下，提取物的最小抑菌浓度（MIC）（抑菌圈平均直径：17.7 mm）显示出它对黑曲霉具有抗真菌活性。