This article reports the first robocasting of a sol–gel based glass ceramic scaffold. Sol–gel bioactive glass powders usually exhibit high volume fractions of meso– and micro–porosities, bad for colloidal processing as this adsorbs significant portion of the dispersing medium, affecting dispersion and flow. We circumvent these practical difficulties, to achieve pastes with particle size distributions, high solids loading and appropriate rheological properties for extrusion through fine nozzles for robocasting. Scaffolds with different macro-pore sizes (300-500 μm) with solid loadings up to 40 vol.% were robocast. The sintered (800 °C, 2 h) scaffolds exhibited compressive strength of 2.5–4.8 MPa, formed hydroxyapatite after 72 h in SBF, and had no cytotoxicity and a considerable MG63 cells viability rate. These features make the scaffolds promising candidates for tissue engineering applications and worthy for further in vivo investigations.

本文报道了基于溶胶-凝胶的玻璃陶瓷支架的首次机器人铸造。溶胶-凝胶生物活性玻璃粉通常具有中等体积和微孔体积分数，这对胶体加工不利，因为它吸收了很大一部分分散介质，影响了分散和流动。我们规避了这些实际困难，以实现具有粒度分布，高固体含量和适当流变特性的糊料，以便通过细喷嘴挤出进行机械浇铸。机器人浇铸了具有不同大孔尺寸（300-500μm），固体含量高达40％（体积）的支架。烧结的支架（800°C，2 h）表现出2.5–4.8 MPa的抗压强度，在SBF中放置72 h后形成羟基磷灰石，并且没有细胞毒性和相当高的MG63细胞存活率。体内调查。