Melamine is commonly used to manufacture the coating of three-piece tin cans. It may migrate into food in the course of storage, threatening the health of consumers. This work aimed to trace the migration of melamine into food simulants (acetic acid, 3% v/v; ethanol, 10% v/v) during coating of three-piece tin cans in order to propose the critical points for food contamination. High-performance liquid chromatography–tandem mass spectrometry was used to detect melamine in samples. The results indicated that the amount of melamine migrating in the overlay–spray process (step 8) is the largest, significantly higher than that of the other processes (P ≤ 0.05). It was also found that the main source of melamine in the packaging of metal containers is the coating. Therefore, the selection of coatings and the optimization of the process can reduce the migration of melamine.

三聚氰胺通常用于制造三片式锡罐的涂层。在储存过程中可能会迁移到食品中，威胁到消费者的健康。这项工作旨在追踪三片罐装锡罐过程中三聚氰胺向食品模拟物中的迁移（乙酸，3％v / v；乙醇，10％v / v），从而提出食品污染的关键点。高效液相色谱-串联质谱法用于检测样品中的三聚氰胺。结果表明，在上层喷涂过程（步骤8）中三聚氰胺的迁移量最大，显着高于其他过程中的三聚氰胺（P≤0.05）。还发现金属容器包装中三聚氰胺的主要来源是涂层。所以，