Cluster randomized trials (CRTs) and individually randomized trials (IRTs) are often pooled together in meta-analyses (MAs) of randomized trials. However, the potential systematic differences in intervention effect estimates between these two trial types has never been investigated. Therefore, we conducted a meta-epidemiological study comparing intervention effect estimates between CRTs and IRTs.

中文翻译：

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整群随机试验与单独随机试验的干预效果估计：一项荟萃流行病学研究

整群随机试验 (CRT) 和单独随机试验 (IRT) 通常在随机试验的荟萃分析 (MA) 中合并在一起。然而，这两种试验类型之间干预效果估计的潜在系统差异从未被调查过。因此，我们进行了一项荟萃流行病学研究，比较 CRT 和 IRT 的干预效果估计。