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Strong C(sp3)-H Arylation by Synergistic Decatungstate Photo-HAT and Nickel Catalysis
Chem ( IF 23.5 ) Pub Date : 2018-11-08 , DOI: 10.1016/j.chempr.2018.10.014
Dong-Mei Yan , Cong Xiao , Jia-Rong Chen

Direct and selective functionalization of sp3 C–H bonds, which are ubiquitous in organic compounds, remains a long-standing challenging reaction. In a recent paper in Nature, MacMillan and colleagues disclosed that the merger of decatungstate photo-HAT and nickel catalysis provided a mild, generally applicable platform for direct and selective arylation of strong C(sp3)–H bonds.



中文翻译:

协同十杂碳酸盐光-HAT和镍催化实现强C(sp 3)-H芳基化

在有机化合物中无处不在的sp 3 C–H键的直接和选择性官能化仍然是一个长期存在的挑战性反应。在《自然》杂志的最近一篇论文中,麦克米伦及其同事披露,去catungstate的光-HAT与镍催化的合并为强C(sp 3)-H键的直接和选择性芳基化提供了一个温和的,普遍适用的平台。

更新日期:2018-11-08
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