The expression of serotonin (5-HT) in the retina was first reported in the sixties. The detection of vesicular monoamine transporter and serotonin receptors in several retinal cells confirm that 5-HT is playing a neuromodulatory role in this structure. Whereas signaling pathways activated by 5-HT receptor binding has been poorly investigated so far, numerous data demonstrated that 5-HT is involved in retinal physiology, retinal physiopathology and photoreceptor survival.

中文翻译：

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视网膜中的血清素

血清素（5-HT）在视网膜中的表达最早是在60年代报道的。在几个视网膜细胞中检测到水泡单胺转运蛋白和5-羟色胺受体证实了5-HT在这种结构中起着神经调节作用。迄今为止，对5-HT受体结合激活的信号通路的研究很少，许多数据表明5-HT参与视网膜生理，视网膜生理病理和光感受器的存活。