Abstract Porous membranes and thin films containing poly-lactic acid (PLA), carvacrol (CRV) and graphene nanoplatelets (GNP) were fabricated by electrospinning and solvent casting at different formulations. The systems were characterized from a mechanical, morphological, calorimetric and spectroscopic point of view. CRV release as a function of time was studied and a mathematical model was used to fit and interpret the data in order to investigate the release mechanism. The results indicate that the incorporation of GNP generally determined a simultaneous strengthening, stiffening and toughening effect, while preserving a good ductility. Furthermore, integrating GNP allowed tuning the amount and kinetics of CRV release, and proved to reduce the initial burst release effect.

中文翻译：

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石墨烯和制备技术对香芹酚从聚乳酸中释放动力学的影响

摘要 通过静电纺丝和溶剂浇铸以不同的配方制备了含有聚乳酸 (PLA)、香芹酚 (CRV) 和石墨烯纳米片 (GNP) 的多孔膜和薄膜。从机械、形态、量热和光谱的角度对系统进行了表征。研究了作为时间函数的 CRV 释放，并使用数学模型拟合和解释数据以研究释放机制。结果表明，GNP 的加入通常决定了同时增强、硬化和增韧效果，同时保持良好的延展性。此外，整合 GNP 可以调整 CRV 释放的数量和动力学，并证明可以降低初始爆发释放效应。