Ten previously undescribed glucosyloxybenzyl succinate derivatives, pleionosides A-J, and fifteen known compounds were isolated from the pseudobulbs of Pleione bulbocodioides (Franch.) Rolfe. Their structures were elucidated by a combination of MS and NMR data, physical and chemical methods and a comparison with known compounds. Furthermore, three compounds exhibited potent hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in in vitro assays, with cell survival rates of 31.89%, 31.52% and 31.97% at 10 μM. Four compounds exhibited moderate antioxidant activity with increasing viability at 10 μM of 36.1%, 45.0%, 25.5% and 20.7%.

中文翻译：

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来自 Pleione billocodioides 假鳞茎的葡糖氧基苄基琥珀酸酯衍生物的保肝活性

10 种以前未描述过的琥珀酸葡糖氧基苄基衍生物、pleionosides AJ 和 15 种已知化合物是从 Pleionebulbocodioides (Franch.) Rolfe 的假鳞茎中分离出来的。它们的结构是通过结合 MS 和 NMR 数据、物理和化学方法以及与已知化合物的比较来阐明的。此外，三种化合物在体外试验中对 N-乙酰基-对氨基苯酚 (APAP) 诱导的 HepG2 细胞损伤表现出有效的保肝活性，在 10 μM 下的细胞存活率分别为 31.89%、31.52% 和 31.97%。四种化合物表现出中等抗氧化活性，在 10 μM 时活力增加，分别为 36.1%、45.0%、25.5% 和 20.7%。