Neuroscience & Biobehavioral Reviews ( IF 8.2 ) Pub Date : 2018-10-28 , DOI: 10.1016/j.neubiorev.2018.10.006 Joyce Whittington , Anthony Holland
We present a review of psychiatric associations with comorbid mental and behavioural disorders affecting people with Prader-Willi syndrome (PWS). This literature review suggests that some assumptions about psychiatric associations of PWS behaviours are unjustified (eg skin picking as OCD) and that genetic aetiology should be considered when making associations between PWS mental and behavioural disorders and psychiatric disorders in the general populationThe literature review also demonstrates the limitations of the studies in terms of small numbers, non-representativeness, and lack of replication.
中文翻译:
Prader-Willi综合征的精神和行为障碍的精神病学概念综述
我们目前对患有影响普拉德-威利综合症(PWS)的合并症的精神和行为障碍的精神病学协会进行综述。这篇文献综述表明,关于PWS行为的精神病学关联的一些假设是不合理的(例如,作为OCD进行皮肤采摘),并且在一般人群中将PWS精神和行为障碍与精神病学联系起来时,应考虑遗传病因。研究的局限性在于数量少,不具有代表性和缺乏重复性。