Objectives

The aim of the study was to evaluate the effect of bioactive glass (45S5 and NbG) suspensions on bond strength (µTBS), hardness, modulus of elasticity, pH and antibacterial activity of the resin-dentin interfaces after 3 months.

Methods

Groups with different concentrations (5% and 20%) of two types of glass (45S5 and NbG), and a control group (distilled water) were studied. Twenty-five extracted human third molars were etched with phosphoric acid. The data from µTBS, hardness and modulus of elasticity data were submitted to two-way ANOVA (suspension vs. time) and Holm-Sidak tests (=0.05). The antimicrobial activity data were analyzed by the Kruskal-Wallis test (α = 5%).

Results

The interactions were significant among groups for µTBS (p = 0.033). Significant reductions in µTBS were observed after 3 months storage in PBS for the Control and 5% NbG Groups. Suspensions with 5% and 20% 45S5 glass and 20% NbG resulted in stable µTBS values and increased hardness after 3 months. Both 20% suspensions (45S5 and NbG) increased the elastic modulus. A significant greater reduction in bacterial growth was observed with the use of 20% 45S5.

Conclusion

Rewetting dentin with the suspension of 20% 45S5 glass prevented the reduction in bond strength; increased hardness; modulus of elasticity of the resin-dentin interface, and demonstrated antibacterial activity against Streptococcus mutans.

中文翻译：

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牙本质用45S5和磷酸氢盐生物活性玻璃进行预处理：对pH值，抗菌，界面机械性能和微拉伸粘合强度的影响。

目标

这项研究的目的是评估3个月后生物活性玻璃（45S5和NbG）悬浮液对粘合强度（µTBS），硬度，弹性模量，pH和抗菌活性的影响。

方法

研究了两种玻璃（45S5和NbG）的浓度不同（5％和20％）的组和对照组（蒸馏水）。用磷酸蚀刻二十五个提取的人类第三磨牙。将来自µTBS的数据，硬度和弹性模量数据提交给双向ANOVA（悬浮液与时间）和Holm-Sidak测试（= 0.05）。通过Kruskal-Wallis检验（α= 5％）分析抗菌活性数据。

结果

对于µTBS，各组之间的相互作用显着（p = 0.033）。对照组和5％NbG组在PBS中保存3个月后，μTBS显着降低。5％和20％的45S5玻璃和20％NbG的悬浮液可产生稳定的µTBS值，并在3个月后增加硬度。两种20％的悬浮液（45S5和NbG）均增加了弹性模量。使用20％45S5可以观察到细菌生长的明显更大减少。

结论

用20％45S5玻璃悬浮液重新润湿牙本质可防止粘结强度降低。硬度增加；树脂-牙本质界面的弹性模量，并证明了对变形链球菌的抗菌活性。