In article number 1801905, Jinlong Shi, Rongqin Huang, Wei Shi, and co‐workers describe a novel drug‐loaded system, OPPD, which uses PEG and OMCN linked to the Pep22 polypeptide targeting the low‐density lipoprotein receptor, that can effectively cross the blood‐brain barrier and target glioma cells, exerting an outstanding therapeutic efficacy via both the near‐infrared photothermal and chemotherapeutic effects of the loaded DOX. The collective findings support the utility of OPPD, a promising drug‐delivery vehicle, for future clinical application in glioma therapy.

中文翻译：

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神经胶质瘤治疗：使用OMCN–PEG–Pep22 / DOX构建的双靶点递送系统介导的联合神经胶质瘤治疗（Small 42/2018）

在1801905号文章中，石金龙，黄荣勤，石维和他的同事描述了一种新型的载药系统OPPD，该系统使用与针对低密度脂蛋白受体的Pep22多肽连接的PEG和OMCN，可以有效地交叉血脑屏障和目标神经胶质瘤细胞，通过装载的DOX的近红外光热作用和化学治疗作用发挥了出色的治疗作用。集体发现支持OPPD（一种有前途的药物递送工具）在神经胶质瘤治疗中的未来临床应用的实用性。