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Norditerpenoid alkaloids from Delphinium pseudoaemulans C. Y. Yang et B. Wang
Phytochemistry ( IF 3.8 ) Pub Date : 2018-12-01 , DOI: 10.1016/j.phytochem.2018.09.010
Wen-Juan Xue , Bo Zhao , Zukela Ruzi , Jiang-Yu Zhao , Haji Akber Aisa

Eight previously undescribed norditerpenoid alkaloids, pseudophnines A-D, pseudorenines A-B, and pseudonidines A-B, together with ten known norditerpenoid alkaloids, tianshanisine E, sharwuphinine B, potanisine A, lycoctonine, delbruline, isondelpheline, delavaines A-B, and shawurenines A-B were isolated from the whole plant of Delphinium pseudoaemulans C. Y. Yang et B. Wang. Their structures were established on the basis of spectroscopic analyses, including HR-ESI-MS, 1D and 2D NMR analysis. Additionally, no cytotoxicity was observed against A549 and HeLa cancer cells of these diterpenoid alkaloids when evaluated in vitro using the MTT method.

中文翻译:

来自花翠雀 CY Yang et B. Wang 的降二萜生物碱

8 种以前未描述的去甲二萜生物碱、伪酚 AD、伪肾素 AB 和伪肾素 AB,连同 10 种已知的降二萜生物碱、天山素 E、沙乌茶碱 B、potanisine A、lycoctonine、delbruline、isondelpheline、delavaines 是从全株 AB 中分离得到的Delphinium pseudoaemulans CY Yang et B. Wang。它们的结构是在光谱分析的基础上建立的,包括 HR-ESI-MS、1D 和 2D NMR 分析。此外,当使用 MTT 方法进行体外评估时,未观察到这些二萜生物碱对 A549 和 HeLa 癌细胞的细胞毒性。
更新日期:2018-12-01
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