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Challenges and Opportunities for Intravital Near-Infrared Fluorescence Imaging Technology in the Second Transparency Window
ACS Nano ( IF 15.8 ) Pub Date : 2018-10-15 00:00:00 , DOI: 10.1021/acsnano.8b07536
Chunyan Li 1, 2 , Qiangbin Wang 1, 2
Affiliation  

The past decade has witnessed rapid technological development on nanoscale probes and imaging optics in the second near-infrared transparency window (NIR-II, 1000–1700 nm). These methods hold great promise for biomedical applications due to their deep penetration through tissues and high fidelity of images. However, applications of these techniques in biomedical research and translational medicine will require a number of issues to be addressed. In this Perspective, we examine the technical challenges for intravital NIR-II fluorescence imaging technology and discuss where the development of this cutting-edge technique fits in the future.

中文翻译:

第二个透明窗口中的活体内近红外荧光成像技术的挑战和机遇

在过去的十年中,在第二个近红外透明窗口(NIR-II,1000-1700 nm)中,纳米级探针和成像光学技术得到了飞速发展。这些方法由于其可穿透组织的深度以及图像的高保真度,因此在生物医学应用中具有广阔的前景。但是,这些技术在生物医学研究和转化医学中的应用将需要解决许多问题。在本《观点》中,我们探讨了活体近红外II荧光成像技术的技术挑战,并讨论了该尖端技术在未来的发展情况。
更新日期:2018-10-15
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