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Palladium‐Catalyzed Synthesis of Indolines from Aroyloxycarbamates through a Tandem Decarboxylative Amination/Heck/Annulation Reaction
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2018-11-15 , DOI: 10.1002/adsc.201800919
Zheng Wang 1 , Peihe Li 1 , Hui Fu 1 , Qipu Dai 1 , Changwen Hu 1
Affiliation  

A novel synthesis of functionalized indolines via a Pd‐catalyzed tandem decarboxylative amination/Heck/annulation reaction has been developed. This process features operational simplicity, mild conditions, and the use of a readily available and environmentally friendly starting material, namely carboxylic acid. Furthermore, the reaction shows good functional group tolerance and chemical selectivity.

中文翻译:

通过串联脱羧胺化/ Heck /环合反应,由芳氧基氨基甲酸酯进行钯催化合成二氢吲哚

通过Pd催化的串联脱羧胺化/ Heck /环化反应,已开发了一种新的功能化二氢吲哚合成方法。该方法的特点是操作简单,条件温和,并使用容易获得且对环境友好的原料,即羧酸。此外,该反应显示出良好的官能团耐受性和化学选择性。
更新日期:2018-11-15
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