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Genome‐Based Identification of a Plant‐Associated Marine Bacterium as a Rich Natural Product Source
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2018-10-15 , DOI: 10.1002/anie.201811589
Reiko Ueoka 1 , Agneya Bhushan 1 , Silke I. Probst 1 , Walter M. Bray 2 , R. Scott Lokey 2 , Roger G. Linington 3 , Jörn Piel 1
Affiliation  

Chemical treasures from the sea were lifted by J. Piel and co‐workers in their Communication (DOI: 10.1002/anie.201805673). A strategy based on biosynthetic gene cluster frequencies in sequenced bacterial genomes can provide information on the chemical richness of unexplored bacteria. The plant‐root‐associated marine bacterium Gynuella sunshinyii was thus uncovered as a source of diverse metabolites with new scaffolds and promising activities.


中文翻译:

基于基因组的植物相关海洋细菌作为丰富天然产物来源的鉴定

J. Piel及其同事在其交流中(DOI:10.1002 / anie.201805673)提起了海上的化学宝藏。一种基于测序细菌基因组中生物合成基因簇频率的策略可以提供有关未探索细菌化学富集的信息。因此发现了与植物根相关的海洋细菌Gynuella sunshinyii,它是具有新支架和有希望的活动的多种代谢产物的来源。
更新日期:2018-10-15
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