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Homogeneous enzyme-free and entropy-driven isothermal fluorescent assay for nucleic acids based on a dual-signal output amplification strategy†
Chemical Communications ( IF 4.3 ) Pub Date : 2018-10-12 00:00:00 , DOI: 10.1039/c8cc07508e
Erhu Xiong 1, 2, 3, 4, 5 , Deshuai Zhen 1, 2, 3, 4, 5 , Ling Jiang 1, 2, 3, 4, 5
Affiliation  

Herein, we developed a homogeneous enzyme-free, ultrasensitive and isothermal fluorescent biosensor for nucleic acid detection with dual-signal output to enhance the reaction rate and sensitivity by combining an entropy-driven catalysis strategy with a catalytic hairpin assembly reaction.

中文翻译:

基于双信号输出扩增策略的核酸均质,无酶和熵驱动的等温荧光测定法

在本文中,我们开发了一种无酶,超灵敏和等温的荧光生物传感器,用于双信号输出的核酸检测,通过将熵驱动的催化策略与催化发夹装配反应相结合来提高反应速率和灵敏度。
更新日期:2018-10-12
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