A new wavelength-tunable and facilely functionable electron donor (D)-acceptor (A) type fluorescent naphthalene core skeleton and its application for cell membrane imaging are reported. The core skeleton shows bright green fluorescence with aldehyde(CHO) moiety at the electron acceptor site, and its emission wavelength is tuned to blue and red by introducing the moiety of nitrile (CN) and dicyanovinyl (CH(CN)₂), respectively, at the acceptor site. In addition, the core skeleton can be readily functionable by introducing a targeting moiety at the extra hydroxyl group. For the first demonstration as a fluorescent probe, a long-chain carbon is introduced and evaluated its bio-imaging ability for the cellular membranes on cells and tissues by using confocal laser scanning microscopy (CLSM) and two-photon microscopy (TPM). The synthesis, photophysical property, and quantum chemical calculations are also identified.

报道了一种新型的波长可调且功能强大的电子供体（D）-受体（A）型荧光萘核心骨架及其在细胞膜成像中的应用。核心骨架显示出在电子受体位点带有醛（CHO）部分的亮绿色荧光，并且通过引入腈（CN）和二氰基乙烯基（CH（CN）₂）的部分将其发射波长调谐为蓝色和红色。），分别在接受者网站上进行。另外，通过在额外的羟基上引入靶向部分，核心骨架可以容易地起作用。对于首次作为荧光探针的演示，通过使用共聚焦激光扫描显微镜（CLSM）和双光子显微镜（TPM）引入了长链碳，并评估了其对细胞和组织上细胞膜的生物成像能力。还确定了合成，光物理性质和量子化学计算。