Sodium carbonate promoted [3 + 2] annulation of α-halohydroxamates and isocyanates,Organic & Biomolecular Chemistry

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Sodium carbonate promoted [3 + 2] annulation of α-halohydroxamates and isocyanates
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2018-10-11 , DOI: 10.1039/c8ob02321b
Shaofa Sun _{1,

2,

3,

4,

5} , Rongxing Chen _{1,

2,

3,

4,

5} , Gangqiang Wang _{1,

2,

3,

4,

5} , Jian Wang _{5,

6,

7,

8}

Affiliation

A new [3 + 2] annulation of readily available α-halohydroxamates and isocyanates has been developed. This protocol allows a rapid assembly of various hydantoins in good to high yields as well as a broad substrate scope and good functional group tolerance.

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