The cytokine interleukin-17A/F (IL-17A/F) not only protects the skin and mucosae against Candida albicans infection in mice and humans but also promotes autoimmunity and autoinflammation in mice. In this issue of Science Signaling, Amatya et al. report that the RNA binding protein Arid5a promotes responses to IL-17A/F through multiple mechanisms.

中文翻译：

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Arid5a使IL-17A / F应答途径不那么干旱

细胞因子白介素17A / F（IL-17A / F）不仅可以保护皮肤和粘膜免受小鼠和人中白色念珠菌的感染，还可以促进小鼠的自身免疫和自身炎症。在本期《科学信号》中，Amatya等人。报道RNA结合蛋白Arid5a通过多种机制促进对IL-17A / F的应答。