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Selected commercial plants: A review of extraction and isolation of bioactive compounds and their pharmacological market value
Trends in Food Science & Technology ( IF 15.1 ) Pub Date : 2018-10-09 , DOI: 10.1016/j.tifs.2018.10.001
Jayanta Kumar Patra , Gitishree Das , Siyoung Lee , Seok-Seong Kang , Han-Seung Shin

Background

Entrepreneurs involved in the commercialization of natural products are currently displaying significant interests in herbal drugs, medicines, and natural product-based herbal products. A broad range of bioactive chemical compounds have been derived from medicinal plants, either in their pure form or as homogenous extracts. As these compounds have broad structural and functional diversities, they offer pharmaceutical companies numerous opportunities for the development of new drug leads. They also represent an excellent source of molecules for the production of food additives, functional foods, nutritional products, and nutraceuticals for the growing number of natural food companies.

Scope and approach

A number of bioactive compounds, including polyphenols, are present in high concentrations in plant species whereas a number of other important compounds such as saponin are present at very low levels. Several identification, extraction, and isolation techniques are currently used to extract bioactive compounds from plants. However, as these techniques are generally laborious and very expensive, there is an urgent need for new advanced techniques for identification, extraction, and isolation of plant bioactive compounds in quantities sufficient for their potential applications in various sectors.

Key findings and conclusions

The aim of this review is to collate and present information on the identification, extraction, and isolation of the most widely used bioactive compounds from selected commercial medicinal plants, thereby providing a useful resource for medicinal scientists and pharmaceutical and food-related industries seeking to generate high yields at low cost to meet market requirements.



中文翻译:

选定的商业工厂:生物活性化合物的提取和分离及其药理市场价值的综述

背景

参与天然产品商业化的企业家目前对草药,药品和基于天然产品的草药产品表现出极大的兴趣。药用植物已经以其纯净形式或均质提取物获得了广泛的生物活性化合物。由于这些化合物具有广泛的结构和功能多样性,因此它们为制药公司提供了许多开发新药的机会。它们还代表了越来越多的天然食品公司用于生产食品添加剂,功能性食品,营养产品和保健食品的分子的极好来源。

范围和方法

许多生物活性化合物(包括多酚)在植物物种中的含量很高,而许多其他重要的化合物(如皂苷)的含量非常低。当前使用几种鉴定,提取和分离技术从植物中提取生物活性化合物。但是,由于这些技术通常是费力的并且非常昂贵,因此迫切需要用于鉴定,提取和分离植物生物活性化合物的新的先进技术,其数量应足以使其在各种领域中的潜在应用。

主要发现和结论

这篇综述的目的是整理和介绍有关从选定的商业药用植物中鉴定,提取和分离最广泛使用的生物活性化合物的信息,从而为寻求产生的药用科学家以及制药和食品相关行业提供有用的资源以低成本高产量满足市场需求。

更新日期:2018-10-09
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