Herein, we report the potential of glycyrrhetinic acid (GA) as an active targeting ligand for hepatocellular carcinoma (HCC) for the development of diagnosis/therapy using small-molecule based approaches. Our preliminary results demonstrated that GA-conjugation to diagnostic/therapeutic counterparts significantly enhanced their HCC targeting ability and excellent therapeutic efficacy.

中文翻译：

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甘草次酸作为肝细胞靶向单位，用于具有增强的细胞类型选择性的抗癌药物递送系统†

在本文中，我们报告了甘草次酸（GA）作为肝细胞癌（HCC）的主动靶向配体的潜力，可用于开发基于小分子方法的诊断/治疗方法。我们的初步结果表明，GA与诊断/治疗对应物的结合显着增强了其HCC靶向能力和出色的治疗功效。