Abstract Commercial diabetes test strips, patterned with a carbon paste, has poor durability and preservability because of using enzyme. Furthermore, carbon paste needs sintering process to get proper conductivity. Therefore, alternative conductive ink and sensing materials are the research theme under consideration lately. Therefore, we demonstrated constructing copper nanowire paste glucose sensor strip (CuNW_GSS) platform to diagnose diabetes nonenzymatically. Copper nanowires (CuNWs) were fabricated by a simple hydrothermal method with a capping agent to preserve the CuNWs from oxidation. Moreover, the CuNW paste could be easily utilized without sintering, and this fabricated paste successfully substituted for the commercial carbon paste pattern due to its high conductivity. CuNWs were used as not only the composition of conductive copper paste but also the sensing material for detecting glucose, which grants high charge transport ability to the glucose sensor, leading to high sensing ability. The limit of detection (LOD) of the CuNW_GSS was 1 nM, which is 40 times higher sensitivity than those of other glucose sensors and the CuNW_GSS also exhibited excellent selectivity. The excellent sensitivity and selectivity clearly indicate the great potential of the CuNW_GSS in diagnosing diabetes easily.

中文翻译：

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用于非酶促葡萄糖检测的高灵敏度铜纳米线导电电极

摘要 商业化的糖尿病试纸，由于使用了酶，因此使用碳糊图案化，耐久性和保存性较差。此外，碳糊需要烧结过程以获得适当的导电性。因此，替代导电墨水和传感材料是最近考虑的研究主题。因此，我们展示了构建铜纳米线糊葡萄糖传感器条（CuNW_GSS）平台以非酶促诊断糖尿病。铜纳米线 (CuNWs) 是通过简单的水热法制造的，使用封端剂来防止 CuNWs 氧化。此外，CuNW 糊可以很容易地使用而无需烧结，并且由于其高导电性，这种制造的糊成功地替代了商业碳糊图案。CuNWs不仅用作导电铜浆的成分，而且用作检测葡萄糖的传感材料，赋予葡萄糖传感器高电荷传输能力，从而产生高传感能力。CuNW_GSS 的检测限 (LOD) 为 1 nM，灵敏度是其他葡萄糖传感器的 40 倍，并且 CuNW_GSS 也表现出出色的选择性。优异的灵敏度和选择性清楚地表明 CuNW_GSS 在轻松诊断糖尿病方面的巨大潜力。其灵敏度比其他葡萄糖传感器高 40 倍，并且 CuNW_GSS 也表现出出色的选择性。优异的灵敏度和选择性清楚地表明 CuNW_GSS 在轻松诊断糖尿病方面的巨大潜力。其灵敏度比其他葡萄糖传感器高 40 倍，并且 CuNW_GSS 也表现出出色的选择性。优异的灵敏度和选择性清楚地表明 CuNW_GSS 在轻松诊断糖尿病方面的巨大潜力。