Long noncoding RNAs (lncRNAs) participate extensively in biological processes of various cancers. The majority of these transcripts are uniquely expressed in differentiated tissues or specific cancer types. lncRNAs are aberrantly expressed in gliomas and exert diverse functions. In this article, we provided an overview of how lncRNAs regulate cellular processes in glioma, enumerated the lncRNAs that may act as glioma biomarkers, and showed their potential clinical implications.

中文翻译：

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靶向胶质瘤中的长非编码RNA：途径的观点

长的非编码RNA（lncRNA）广泛参与各种癌症的生物学过程。这些转录物中的大多数在分化的组织或特定的癌症类型中独特表达。lncRNA在神经胶质瘤中异常表达并发挥多种功能。在本文中，我们概述了lncRNA如何调控神经胶质瘤中的细胞过程，列举了可能充当神经胶质瘤生物标志物的lncRNA，并显示了其潜在的临床意义。