Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Selective Deprotection of N-Tosyl Alkoxyamines Using Bistrifluoromethane Sulfonimide: Formation of Oxime Ethers
Synlett ( IF 1.7 ) Pub Date : 2018-10-02 , DOI: 10.1055/s-0037-1610298 Janine Cossy 1 , Mohamed Azizi
Synlett ( IF 1.7 ) Pub Date : 2018-10-02 , DOI: 10.1055/s-0037-1610298 Janine Cossy 1 , Mohamed Azizi
Affiliation
The detosylation of N-tosyl alkoxyamines was realized by treatment with benzaldehyde and bistrifluoromethane sulfonimide as the catalyst to afford the corresponding oxime ethers. The reaction is chemoselective as N-tosyl amines are not deprotected. A mechanism is proposed for this deprotection.
中文翻译:
使用双三氟甲烷磺酰亚胺选择性脱保护 N-甲苯磺酰基烷氧基胺:肟醚的形成
N-甲苯磺酰基烷氧基胺的脱甲苯磺酰化反应是通过以苯甲醛和双三氟甲磺酰亚胺为催化剂处理得到相应的肟醚。该反应具有化学选择性,因为 N-甲苯磺胺未脱保护。针对这种脱保护提出了一种机制。
更新日期:2018-10-02
中文翻译:
使用双三氟甲烷磺酰亚胺选择性脱保护 N-甲苯磺酰基烷氧基胺:肟醚的形成
N-甲苯磺酰基烷氧基胺的脱甲苯磺酰化反应是通过以苯甲醛和双三氟甲磺酰亚胺为催化剂处理得到相应的肟醚。该反应具有化学选择性,因为 N-甲苯磺胺未脱保护。针对这种脱保护提出了一种机制。