The field of supramolecular chemistry has its foundation in molecular recognition and selective binding of guest molecules, often with remarkably strong binding affinities. The field evolved to leverage these favorable interactions between the host and its guest to catalyze simple, often biomimetic transformations. Drawing inspiration from these early studies, self-assembled supramolecular hosts continue to capture a significant amount of interest toward their development as catalysts for increasingly complex transformations. Nature often relies on microenvironments, derived from complex tertiary structures and a well-defined active site, to promote reactions with remarkable rate acceleration, substrate specificity, and product selectivity. Similarly, supramolecular chemists have become increasingly intrigued by the prospect that self-assembly of molecular components might generate defined and spatially segregated microenvironments that can catalyze complex transformations.

中文翻译：

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自组装四面体主体作为超分子催化剂

超分子化学领域的基础是分子识别和客体分子的选择性结合，通常具有非常强的结合亲和力。该领域得以发展，以利用宿主及其来宾之间的这些有利相互作用来催化简单的，通常是仿生的转化。从这些早期研究中汲取灵感，自组装超分子宿主作为其日益复杂的转化的催化剂，继续对其开发产生了极大的兴趣。大自然通常依靠源自复杂三级结构和明确定义的活性位点的微环境来促进反应，并具有显着的速率加速，底物特异性和产物选择性。相似地，