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Portable glucose meter: trends in techniques and its potential application in analysis
Analytical and Bioanalytical Chemistry ( IF 3.8 ) Pub Date : 2018-10-02 , DOI: 10.1007/s00216-018-1361-7
Linan Zhang , Chunchuan Gu , Huan Ma , Langlang Zhu , Jiajun Wen , Hanxiao Xu , Hongying Liu , Lihua Li

A blood glucose meter is an electronic medical device used for determining the concentration of glucose in blood. These meters have undergone five phases of development: washed blood glucose meters, wiped blood glucose meters, colorimetric blood glucose meters, electrochemical blood glucose meters, and micro, multiple site blood glucose meters. Thanks to their speed, portability, low cost, and easy operation, blood glucose meters have been widely available for use in clinical diagnosis. Recently, coupling of target recognition elements (antibody–antigen recognition, nucleic acid hybridization, enzyme recognition, and click chemistry) with signal transduction and amplification strategies (glucose-generating enzymes, nicotinamide adenine dinucleotide (NADH)-generating enzymes, encapsulated glucose, nanomaterials, and cyclic amplification of DNA) has allowed various targets to be determined via the relationship between the signal of the blood glucose meter and the concentration of targets. In this paper, a brief review of the development and mechanism of blood glucose meters is given first. Then, more details on the application of blood glucose meters in analysis are described, including biomedical analysis, food analysis, and environmental analysis. Finally, the prospect of future development of blood glucose meters is also discussed.

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中文翻译:

便携式血糖仪:技术趋势及其在分析中的潜在应用

血糖仪是用于确定血液中葡萄糖浓度的电子医疗设备。这些血糖仪已经经历了五个阶段的发展:冲洗血糖仪,擦拭血糖仪,比色血糖仪,电化学血糖仪以及微型,多位置血糖仪。由于它们的速度,便携性,低成本和易于操作,血糖仪已广泛用于临床诊断。最近,目标识别元件(抗体-抗原识别,核酸杂交,酶识别和点击化学)与信号转导和扩增策略(产生葡萄糖的酶,产生烟酰胺腺嘌呤二核苷酸(NADH)的酶,包封的葡萄糖,纳米材料)结合在一起,(DNA的循环扩增)已经允许通过血糖仪的信号与靶标浓度之间的关系来确定各种靶标。本文首先简要介绍了血糖仪的发展及其机理。然后,将详细介绍血糖仪在分析中的应用,包括生物医学分析,食品分析和环境分析。最后,还讨论了血糖仪的未来发展前景。描述了血糖仪在分析中的更多详细信息,包括生物医学分析,食品分析和环境分析。最后,还讨论了血糖仪的未来发展前景。描述了血糖仪在分析中的更多详细信息,包括生物医学分析,食品分析和环境分析。最后,还讨论了血糖仪的未来发展前景。

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更新日期:2018-10-02
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