A single-step multi-level supramolecular system for cancer sonotheranostics.,Nanoscale Horizons

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A single-step multi-level supramolecular system for cancer sonotheranostics.
Nanoscale Horizons ( IF 8.0 ) Pub Date : 2018-10-15 , DOI: 10.1039/c8nh00276b
Huirong Lin ₁ , Shuang Li , Junqing Wang , Chengchao Chu , Yang Zhang , Xin Pang , Peng Lv , Xiaoyong Wang , Qingliang Zhao , Junjie Chen , Hongmin Chen , Wen Liu , Xiaoyuan Chen , Gang Liu

Affiliation

A multi-level supramolecular system produced by single-step Fe3+-mediated ionic crosslinking self-assembly can overcome the critical issues of current sonodynamic therapy (SDT) and address the need to monitor therapeutic effects in vivo with a non-invasive approach. This rational design of organic sonosensitizer-based formulation shows great potential for clinical SDT against deep-seated cancer.

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