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A single-step multi-level supramolecular system for cancer sonotheranostics.
Nanoscale Horizons ( IF 8.0 ) Pub Date : 2018-10-15 , DOI: 10.1039/c8nh00276b
Huirong Lin 1 , Shuang Li , Junqing Wang , Chengchao Chu , Yang Zhang , Xin Pang , Peng Lv , Xiaoyong Wang , Qingliang Zhao , Junjie Chen , Hongmin Chen , Wen Liu , Xiaoyuan Chen , Gang Liu
Affiliation  

A multi-level supramolecular system produced by single-step Fe3+-mediated ionic crosslinking self-assembly can overcome the critical issues of current sonodynamic therapy (SDT) and address the need to monitor therapeutic effects in vivo with a non-invasive approach. This rational design of organic sonosensitizer-based formulation shows great potential for clinical SDT against deep-seated cancer.

中文翻译:

用于癌症超声治疗的单步多级超分子系统。

由单步Fe3 +介导的离子交联自组装产生的多级超分子系统可以克服当前的声动力学疗法(SDT)的关键问题,并满足使用非侵入性方法监测体内治疗效果的需求。这种基于有机声敏剂的配方的合理设计显示了针对深层癌症的临床SDT的巨大潜力。
更新日期:2018-10-01
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