A novel colorimetric fluorescent chemosensor TP1 with a D-π-A structure for the detection of (cyanide) CN⁻ has been developed. TP1 is capable of showing high selectivity and sensitivity towards CN⁻ over a wide range of other interfering anions. After reaction with CN⁻, TP1 shows a significant blue-shift of absorption peak from 514 to 437 nm, which induces color changes from amaranth to yellow. Non-fluorescent TP1 upon interaction with CN⁻ exhibits a ca. 17-fold fluorescence enhancement at 551 nm, resulting in strong orange emission. The sensing mechanism of TP1 recognizes CN⁻ which undergoes a nucleophilic addition reaction. Moreover, the detection limit of the probe TP1 towards CN⁻ is 1.4 × 10⁻⁸ M, which is far lower than the WHO guideline of 1.9 μM cyanide for drinking water. In addition, the cell imaging experiments certify that TP1 can be successfully applied as a bioimaging agent for monitoring CN⁻ in pheochromocytoma cell (PC12).

一种新颖的比色荧光化学传感器TP1与用于检测的（氰）一个d-π-A结构CN ^-已经研制成功。TP1能够显示朝向CN的高选择性和灵敏性的^-在宽范围的其他干扰的阴离子。与CN反应后^- ，TP1吸收峰的示出了显著蓝移从514到437纳米，其诱导从苋菜颜色变为黄色。非荧光TP1在与CN交互^-表现出约 在551 nm处荧光增强17倍，导致强烈的橙色发射。的感应机制TP1识别CN ^-经历亲核加成反应。此外，探针的检测极限TP1向CN ^-是1.4×10 ^-8  M，其远低于1.9μM氰化物的WHO指南饮用水。此外，细胞成像实验证明TP1可以成功地应用于作为生物成像剂用于监测CN ^-在嗜铬细胞瘤细胞（PC12）。