New fluorescent nanocarriers based on the POSS (polyhedral octasilsesquioxanes) nanocage labelled with the photosensitive cationic phenosafranin dye (PSF) provide a useful means for in vitro imaging. In this study, a simply reaction for preparing biocompatible POSS-PSF nanohybrids was successfully developed using a coupling (N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride) agent in a one-step reaction between the amino group of dye molecules and anhydride residues of POSS. The first time are reported fluorescent nanodots as a unique POSS-PSF nanostructure easily transferable by cellular pores due to their cationic charges, which are new intercalative DNA agents useful in anticancer therapies and cellular imaging.

基于用光敏阳离子苯那弗兰宁染料（PSF）标记的POSS（多面体八聚倍半硅氧烷）纳米笼的新型荧光纳米载体为体外成像提供了有用的手段。在这项研究中，仅仅一用于制备生物相容的POSS-PSF纳米复合物反应，使用联接器（研制成功ñ - - （3-二甲氨基丙基）ñ剂中的氨基的染料分子之间的一步反应'-ethylcarbodiimide盐酸盐） POSS的酸酐残基。首次报道的荧光纳米点是一种独特的POSS-PSF纳米结构，由于其阳离子电荷而易于被细胞孔转移，这是可用于抗癌治疗和细胞成像的新型嵌入DNA试剂。