Chronic Liquid Fructose, but not Glucose, Supplementation Selectively Induces Visceral Adipose Tissue Leptin Resistance and Hypertrophy in Female Sprague‐Dawley Rats,Molecular Nutrition & Food Research

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Chronic Liquid Fructose, but not Glucose, Supplementation Selectively Induces Visceral Adipose Tissue Leptin Resistance and Hypertrophy in Female Sprague‐Dawley Rats
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-10-11 , DOI: 10.1002/mnfr.201800777
Gemma Sangüesa _{1,

2} , Núria Roglans _{1,

2,

3} , José Carlos Montañés ₁ , Miguel Baena _{1,

2} , Ana Magdalena Velázquez ₁ , Rosa María Sánchez _{1,

2,

3} , Marta Alegret _{1,

2,

3} , Juan Carlos Laguna _{1,

2,

3}

Affiliation

The effect of chronic supplementation with simple‐sugar solutions on leptin signaling in liver, hypothalamus, and visceral white adipose tissue (vWAT) is studied, which is designed to mimic the temporal pattern of consumption by humans.

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