The objective of the study was to evaluate the effect of individual quarter dry-off in management of subclinical mastitis on clinical development, behavior during milking, and short-term production loss. The study was conducted as a controlled randomized trial in 5 commercial organic dairy herds. Seventy cows meeting the inclusion criteria were randomly allocated to 1 of 2 treatments: individual quarter dry-off (QDO) or continued milking. The inclusion criteria constituted an increase in somatic cell count from below to above 400,000 cells/mL at milk recording and identification of a quarter scoring of at least 3 and higher than the remaining quarters at California mastitis testing (scale 1–5). Quarters were evaluated clinically for atrophy, swelling, firmness, signs of pain, and milk leakage, and rectal temperature of the cows was measured. Behavior during milking was assessed as average frequency of hind limb tripping and kicking during milking obtained by registrations on video recordings. Milk production loss was estimated based on average daily milk yield for 19 d subsequent to treatment start, with reference to average daily milk yield in 19 d before treatment. The QDO treatment was associated with quarter swelling and increased quarter firmness around d 10 from treatment start and with quarter atrophy around d 40 from treatment start. However, around d 40 from treatment start 35% of the dried-off quarters remained nonatrophic and only 6% of the quarters were completely dry. The QDO was associated with signs of pain related to the dried-off quarter. No obvious effects on behavior during milking of QDO treatment was observed. On average the production loss associated with QDO was 4.1 kg/d (95% confidence interval: 3.1–5.0) greater than for continued milking. The production loss depended on parity, days in milk, and prior yield on the quarter subjected to dry-off (Q1). The production loss increased with increasing prior yield on Q1. For the majority of cows the increase in production loss was below 1 kg of milk/d when the prior yield on Q1 increased by 1 kg of milk/d, demonstrating a compensatory production potential of the nontreated quarters. Early lactation multiparous cows showed the greatest compensatory potential. Further studies into the effect on welfare, cure rates, and transmission are needed to determine the feasibility of individual quarter dry-off.

这项研究的目的是评估亚临床乳腺炎的处理中每季度干燥对临床发展，挤奶期间行为和短期生产损失的影响。该研究是在5个商业有机奶牛群中进行的随机对照试验。将符合纳入标准的70头母牛随机分配至以下2种处理方法中的1种：单独的四分之一干（QDO）或继续挤奶。入选标准包括在牛奶记录时，体细胞计数从低于40万个细胞/ mL增加到高于40万个细胞/ mL；在加利福尼亚乳腺炎测试中，四分之一的得分至少为3，高于其余四分之一（等级1-5）。在临床上对宿舍进行评估以评估其萎缩，肿胀，坚硬，疼痛的迹象和漏奶，并测量母牛的直肠温度。挤奶期间的行为被评估为通过录像记录获得的挤奶期间后肢绊倒和踢动的平均频率。根据治疗开始后19 d的平均每日产奶量，并参考治疗前19 d的平均每日产奶量，估算出产奶量损失。QDO治疗与治疗开始后第10天左右的四分之一肿胀和四分之一硬度增加有关，并且与治疗开始后第40天的四分之一萎缩有关。但是，从治疗开始约40天，35％的干燥处仍然是非萎缩的，只有6％的处所完全干燥。QDO与干quarter的季度有关的疼痛迹象相关。在QDO处理的挤奶过程中，没有观察到对行为的明显影响。平均而言，QDO带来的生产损失要比持续挤奶多4.1 kg / d（95％置信区间：3.1–5.0）。生产损失取决于产值，牛奶天数以及经过干燥处理的季度的先前产量（Q1）。随着第一季度先前产量的增加，生产损失增加。对于大多数奶牛，当第一季度先前的产量增加1公斤牛奶/天时，生产损失的增加低于1公斤牛奶/天，这表明未经处理的鸡舍的补偿性生产潜力。早期泌乳的多头母牛表现出最大的补偿潜力。需要进一步研究对福利，治愈率和传播的影响，以确定每个季度干燥的可行性。生产损失取决于产值，牛奶天数以及经过干燥处理的季度的先前产量（Q1）。随着第一季度先前产量的增加，生产损失增加。对于大多数奶牛，当第一季度先前的产量增加1公斤牛奶/天时，生产损失的增加低于1公斤牛奶/天，这表明未经处理的鸡舍的补偿性生产潜力。早期泌乳的多头母牛表现出最大的补偿潜力。需要进一步研究对福利，治愈率和传播的影响，以确定每个季度干燥的可行性。生产损失取决于产值，牛奶天数以及经过干燥处理的季度的先前产量（Q1）。随着第一季度先前产量的增加，生产损失增加。对于大多数奶牛，当第一季度先前的产量增加1公斤牛奶/天时，生产损失的增加低于1公斤牛奶/天，这表明未经处理的鸡舍的补偿性生产潜力。早期泌乳的多头母牛表现出最大的补偿潜力。需要进一步研究对福利，治愈率和传播的影响，以确定每个季度干燥的可行性。对于大多数奶牛，当第一季度先前的产量增加1公斤牛奶/天时，生产损失的增加低于1公斤牛奶/天，这表明未经处理的鸡舍的补偿性生产潜力。早期泌乳的多头母牛表现出最大的补偿潜力。需要进一步研究对福利，治愈率和传播的影响，以确定每个季度干燥的可行性。对于大多数奶牛，当第一季度先前的产量增加1公斤牛奶/天时，生产损失的增加低于1公斤牛奶/天，这表明未经处理的鸡舍的补偿性生产潜力。早期泌乳的多头母牛表现出最大的补偿潜力。需要进一步研究对福利，治愈率和传播的影响，以确定每个季度干燥的可行性。