Triflimide (HNTf2) in Organic Synthesis,Chemical Reviews

当前位置： X-MOL 学术 › Chem. Rev. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Triflimide (HNTf2) in Organic Synthesis
Chemical Reviews ( IF 51.4 ) Pub Date : 2018-09-25 00:00:00 , DOI: 10.1021/acs.chemrev.8b00279
Wanxiang Zhao ₁ , Jianwei Sun ₂

Affiliation

Triflimide (HNTf₂) is a commercially available and highly versatile super Brønsted acid. Owing to its strong acidity as well as good compatibility with organic solvents, it has been widely employed as an exceptional catalyst, promoter, or additive in a wide range of organic reactions. On many occasions, triflimide has been demonstrated to outperform triflic acid (TfOH). The uniquely outstanding performance of triflimide also benefits from the low nucleophilicity and noncoordinating property of its conjugate base (Tf₂N^–). Therefore, it has been employed as a precursor toward a variety of cationic metal complexes or organic intermediates with enhanced reactivity or catalytic activity. In this Review, we describe these features and applications of triflimide in organic synthesis, including its synthesis, physical properties, and role as catalyst or promoter in organic reactions. At the end of this Review, another closely related reagent, triflidic acid (HCTf₃), is also briefly introduced.

中文翻译：

有机合成中的三氟甲酰亚胺（HNTf ₂）

三氟甲酰亚胺（HNTf ₂）是一种可商购的，用途广泛的超级布朗斯台德酸。由于其强酸度以及与有机溶剂的良好相容性，它已被广泛用作各种有机反应中的特殊催化剂，助催化剂或添加剂。在许多情况下，三氟甲酰亚胺已被证明优于三氟甲磺酸（TfOH）。三氟甲酰亚胺独特的杰出性能还得益于其共轭碱（Tf ₂ N ^–）。因此，它已被用作具有增强的反应性或催化活性的各种阳离子金属络合物或有机中间体的前体。在这篇综述中，我们描述了三氟甲酰亚胺在有机合成中的这些特征和应用，包括其合成，物理性质以及在有机反应中作为催化剂或促进剂的作用。在本综述的最后，还简要介绍了另一种密切相关的试剂三氟甲磺酸（HCTf ₃）。

更新日期：2018-09-25

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11