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Studying the real-time interplay between triglyceride digestion and lipophilic micronutrient bioaccessibility using droplet microfluidics. 2 application to various oils and (pro)vitamins
Food Chemistry ( IF 8.5 ) Pub Date : 2018-09-25 , DOI: 10.1016/j.foodchem.2018.09.126
Hoang Thanh Nguyen , Mélanie Marquis , Marc Anton , Sébastien Marze

The kinetics of micellar solubilization of lipophilic micronutrients (bioaccessibility) in relation with triglyceride digestion remains poorly known. To study this interplay in real-time, a droplet microfluidic method was designed and used as reported in the first part of this article series. In this second part, the interplay between the micellar solubilization of (pro)vitamins (beta-carotene or retinyl palmitate) and the digestion of triglyceride oils (tricaprylin TC, or high-oleic sunflower seed oil HOSO, or fish oil FO) during simulated gastrointestinal digestion was investigated. The relation between the release of both micronutrients and of triglyceride lipolytic products was found to be non-linear. The kinetics of beta-carotene was found to follow the kinetics of lipolytic products, depending on the oil type (TC > HOSO > FO). The effect of the gastric phase on the intestinal phase was also found to follow this order, mostly due to partial lipolysis during the gastric phase.



中文翻译:

使用液滴微流控技术研究甘油三酸酯消化与亲脂性微营养素生物可及性之间的实时相互作用。2应用于各种油和(原)维生素

与甘油三酸酯消化有关的脂溶性微量营养素的胶束增溶动力学(生物可及性)仍然知之甚少。为了实时研究这种相互作用,按照本系列文章第一部分的报道,设计并使用了微滴微流控方法。在第二部分中,模拟过程中(原)维生素(β-胡萝卜素或棕榈酸视黄酯)的胶束增溶作用与甘油三酸酯油(tricaprylin TC或高油酸葵花籽油HOSO或鱼油FO)的消化之间的相互作用。对胃肠道的消化进行了研究。发现微量营养素和甘油三酸酯脂解产物的释放之间的关系是非线性的。发现β-胡萝卜素的动力学遵循脂解产物的动力学,这取决于油的类型(TC> HOSO> FO)。

更新日期:2018-09-25
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