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Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets
Food and Chemical Toxicology ( IF 4.3 ) Pub Date : 2018-09-22 , DOI: 10.1016/j.fct.2018.09.049
S. Chereau , P. Rogowsky , B. Laporte , X. Coumoul , A. Moing , N. Priymenko , P. Steinberg , R. Wilhelm , J. Schiemann , B. Salles , F. Richard-Forget

We analyzed a comprehensive set of contaminants in MON810 and NK603 genetically modified (GM) maize, and their non-GM counterparts, used in a rat feeding study (the GMO90 + project). Both the maize grains and the manufactured pellets were characterized. Only minor differences in contaminant levels between GM and corresponding non-GM harvests were evidenced. Fumonisin and deoxynivalenol mycotoxins were the pollutants present in the highest amounts, with concentrations that were however largely below acceptance reference values. Our data reporting slightly lower levels of fumonisin in MON810 compared to its non-GM counterpart corroborate the lower susceptibility of insect resistant Bt maize to fumonisin-producing fungi. Traces of glyphosate (0.016 mg/kg) were evidenced in grains from NK603 treated crops. Regarding the pellets, analysis of more than 650 potentially toxic substances revealed low amounts of various mycotoxins, pesticides and heavy metals. Concentrations of contaminants quantified in the pellets were however far below the maximum level of residues values set by regulatory agencies, and no substantial differences in contaminants between GM and non-GM pellets were observed. Moreover, when comparing the contamination status of grains and pellets, we demonstrate yet again that characterizing the grains is actually not sufficient to foresee the quality of the produced pellets.



中文翻译:

大鼠喂养试验:对转基因玉米和所得颗粒中污染物的全面评估

我们分析了用于老鼠喂养研究(GMO90 +项目)的MON810和NK603转基因(GM)玉米及其非转基因玉米中的一整套污染物。玉米粒和制成的粒料均被表征。仅在转基因和相应的非转基因收获之间污染物水平上的细微差别被证明。伏马毒素和脱氧雪腐酚霉菌毒素是最高含量的污染物,但是其浓度大大低于可接受的参考值。我们的数据报道,与非转基因同类产品相比,MON810中的伏马毒素含量略低,这证实了抗虫Bt玉米对产生伏马毒素的真菌的敏感性较低。在NK603处理过的农作物的谷物中发现了草甘膦(0.016 mg / kg)的痕迹。关于颗粒 对650多种潜在有毒物质的分析表明,各种霉菌毒素,农药和重金属的含量较低。然而,颗粒中所定量的污染物浓度远远低于监管机构设定的最大残留量水平,并且在GM和非GM颗粒之间未观察到污染物的实质性差异。此外,当比较谷物和颗粒的污染状况时,我们再次证明,表征谷物实际上不足以预见所生产颗粒的质量。并没有观察到GM和非GM颗粒之间的污染物有实质性差异。此外,当比较谷物和颗粒的污染状况时,我们再次证明,表征谷物实际上不足以预见所生产颗粒的质量。并没有观察到GM和非GM颗粒之间的污染物有实质性差异。此外,当比较谷物和颗粒的污染状况时,我们再次证明,表征谷物实际上不足以预见所生产颗粒的质量。

更新日期:2018-09-22
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