Visible Light‐Induced Aerobic Oxidative −H Arylation of Glycine Derivatives,Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Visible Light‐Induced Aerobic Oxidative −H Arylation of Glycine Derivatives
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2018-10-22 , DOI: 10.1002/adsc.201801018
Shilin Li ₁ , Xiaorong Yang ₁ , Yunwei Wang ₁ , Huang Zhou ₁ , Boyang Zhang ₁ , Ganxing Huang ₁ , Yuan Zhang ₁ , Ying Li ₁

Affiliation

A direct aerobic oxidative dehydrogenative coupling reaction of glycine derivatives with electron‐rich arenes has been accomplished via the synergistic combination of organic‐dye mediated photoredox catalysis and Lewis acid catalysis. This process exhibits good tolerance of functional groups and provides rapid synthesis of arylglycine derivatives at room temperature under an air atmosphere. Moreover, this protocol could be performed on a 10 mmol scale, without obvious reduction of the yield.

中文翻译：

甘氨酸衍生物的可见光诱导的好氧氧化-H酰化

甘氨酸衍生物与富电子芳烃的直接好氧氧化脱氢偶联反应是通过有机染料介导的光氧化还原催化和路易斯酸催化的协同作用而完成的。该方法表现出对官能团的良好耐受性，并且在室温下在空气气氛下提供芳基甘氨酸衍生物的快速合成。此外，该方案可以在10 mmol规模下进行，而收率没有明显降低。

更新日期：2018-10-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11