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Bypassing Kinase Signaling in Mammalian Cells
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2018-09-20 , DOI: 10.1016/j.chembiol.2018.09.001
Heinz Neumann 1
Affiliation  

Serine phosphorylation is frequently used to control the activity of proteins. Eukaryotic cells employ cascades of these phosphorylation events to encode and distribute information. In this issue ofCell Chemical Biology,Beránek et al. (2018)report the creation of a system to genetically incorporate phosphoserine in mammalian cells, thereby circumventing upstream kinase signaling.

中文翻译:


绕过哺乳动物细胞中的激酶信号传导



丝氨酸磷酸化经常用于控制蛋白质的活性。真核细胞利用这些磷酸化事件的级联来编码和分发信息。在本期《细胞化学生物学》中,Beránek 等人。 (2018) 报告创建了一种系统,可以通过基因方式将磷酸丝氨酸整合到哺乳动物细胞中,从而规避上游激酶信号传导。
更新日期:2018-09-20
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