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Bisphenol-A in breast adipose tissue of breast cancer cases and controls
Environmental Research ( IF 7.7 ) Pub Date : 2018-08-31 , DOI: 10.1016/j.envres.2018.08.033
Katherine W. Reeves , Sallie Schneider , Jingchuan Xue , Kurunthachalam Kannan , Holly Mason , Melissa Johnson , Grace Makari-Judson , Mary Díaz Santana

We evaluated whether bisphenol-A (BPA) could be quantified in breast adipose tissue samples provided by 36 breast cancer mastectomy patients and 14 reduction mammoplasty patients. Samples of breast adipose tissue were collected and BPA concentration was quantified using HPLC-ESI-MS/MS. BPA was detectable above the limit of quantitation of 0.38 ng/g in 30.6% of samples. BPA concentrations varied within- and between breasts and were similar between cases and controls (0.39 vs 0.41 ng/g, p = 0.74).



中文翻译:

乳腺癌乳腺组织中双酚A的情况及对策

我们评估了双酚A(BPA)是否可以在由36例乳腺癌乳房切除术患者和14例减少乳腺成形术患者提供的乳腺脂肪组织样品中进行定量。收集乳房脂肪组织样品,并使用HPLC-ESI-MS / MS对BPA浓度进行定量。在30.6%的样品中,可检测到的BPA超过0.38 ng / g的定量限。乳房内和乳房之间的BPA浓度各不相同,病例与对照组之间的BPA浓度相似(0.39对0.41 ng / g,p = 0.74)。

更新日期:2018-08-31
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