Enantiomerically-enriched secondary trichloromethyl-alcohols react with aryl amines to give enantiomerically-enriched α-N-arylamino-acid derivatives. The intermediate acid chlorides can react in situ with aryl or, regioselectively, with alkyl amines to give aryl or alkyl α-N-arylamino amides.

中文翻译：

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通过Jocic型反应合成对映体富集的N-芳基氨基酰胺

对映体富集的仲三氯甲基醇与芳基胺反应，得到对映体富集的α - N-芳基氨基酸衍生物。中间体酰氯可与芳基原位反应，或与烷基胺区域选择性地反应，得到芳基或烷基α- N-芳基氨基酰胺。