当前位置: X-MOL 学术Org. Process Res. Dev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Catalytic Static Mixers for the Continuous Flow Hydrogenation of a Key Intermediate of Linezolid (Zyvox)
Organic Process Research & Development ( IF 3.4 ) Pub Date : 2018-09-14 00:00:00 , DOI: 10.1021/acs.oprd.8b00153
James Gardiner 1 , Xuan Nguyen 1 , Charlotte Genet 1 , Mike D. Horne 2 , Christian H. Hornung 1 , John Tsanaktsidis 1
Affiliation  

Catalytic static mixers (CSMs) were used for the efficient preparation of a key intermediate of the antimicrobial drug linezolid (Zyvox). The approach combines 3D printing and additive manufacturing techniques with continuous flow processing to produce a general method for catalytic hydrogenations and the rapid production of the target molecule without the need for catalyst removal or recovery.

中文翻译:

催化静态混合器,用于对利奈唑胺(Zyvox)的关键中间体进行连续流加氢

催化静态混合器(CSM)用于有效制备抗菌药物利奈唑胺(Zyvox)的关键中间体。该方法将3D打印和增材制造技术与连续流处理相结合,以产生催化加氢和快速生产目标分子的通用方法,而无需去除或回收催化剂。
更新日期:2018-09-14
down
wechat
bug