当前位置: X-MOL 学术Chem. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Redox-triggered cascade dearomative cyclizations enabled by hexafluoroisopropanol†
Chemical Science ( IF 7.6 ) Pub Date : 2018-09-13 00:00:00 , DOI: 10.1039/c8sc03339k
Shuai-Shuai Li 1 , Xintong Lv 1 , Didi Ren 1 , Chang-Lun Shao 2 , Qing Liu 3 , Jian Xiao 1
Affiliation  

An unprecedented cascade dearomative cyclization through hydrogen-bonding-assisted hydride transfer is realized. The aggregate effect of HFIP enables the rapid buildup of polycyclic amines directly from phenols and o-aminobenzaldehydes via a cascade dearomatization/rearomatization/dearomatization sequence. This unique transformation addressed the drawbacks of hydride transfer-involved redox-neutral reactions.

中文翻译:


由六氟异丙醇实现的氧化还原触发级联脱芳香环化†



通过氢键辅助氢化物转移实现了前所未有的级联脱芳环化。 HFIP 的聚合效应使得能够通过级联脱芳构化/重芳构化/脱芳构化序列直接从酚和氨基苯甲醛快速生成多环胺。这种独特的转变解决了涉及氢化物转移的氧化还原中性反应的缺点。
更新日期:2018-09-13
down
wechat
bug