AbstractA porphyrinic metal–organic framework (PCN-224) was fabricated and used as an adsorbent for solid-phase extraction of ultratrace levels of polar sulfonamide antibiotics from food and drinking waters. The PCN-224 was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and powder X-ray diffraction analyses. Parameters affecting the extraction efficiency were optimized. The sulfonamides were quantified by liquid chromatography-tandem mass spectrometry. Figures of merit include (a) low limits of detection (0.07–0.47 ng·L−1), (b) wide linear ranges (0.5–2000 ng·L−1), and (c) good repeatabilities (2.8%–6.7%) and reproducibilities (1.7%–5.1%). The method was successfully applied to the determination of sulfonamides in food and drinking water samples. Graphical abstractA Zr(IV)-based porphyrinic metal−organic framework (PCN-224) was synthesized from a Zr6 cluster and the H2TCPP ligand. It was used for solid-phase extraction of sulfonamides from food and drinking water samples coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for determination.

中文翻译：

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一种基于 Zr(IV) 的卟啉金属有机骨架作为固相吸附剂，用于在通过 LC-MS 定量之前提取磺酰胺

摘要制备了卟啉金属有机骨架 (PCN-224) 并将其用作固相萃取食品和饮用水中超痕量极性磺酰胺抗生素的吸附剂。PCN-224 通过扫描电子显微镜、傅里叶变换红外光谱和粉末 X 射线衍射分析进行表征。对影响提取效率的参数进行了优化。通过液相色谱-串联质谱法对磺胺类药物进行定量。品质因数包括 (a) 低检测限 (0.07–0.47 ng·L−1)，(b) 宽线性范围 (0.5–2000 ng·L−1)，以及 (c) 良好的重复性 (2.8%–6.7 %) 和再现性 (1.7%–5.1%)。该方法已成功应用于食品和饮用水样品中磺胺类药物的测定。图形摘要从 Zr6 簇和 H2TCPP 配体合成了基于 Zr(IV) 的卟啉金属有机骨架 (PCN-224)。它用于固相萃取食品和饮用水样品中的磺胺类药物，并结合液相色谱-串联质谱 (LC-MS/MS) 进行测定。